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Hydrastinine


Hydrastinine
Systematic (IUPAC) name
1,3-dioxolo(4,5-g)isoquinolin-5-ol, 5,6,7,8-tetrahyro-6-methyl-5,6,7,8-Tetrahydro-6-methyl-1,3-dioxolo(4,5-g)isoquinolin-5-ol
Identifiers
CAS number	6592-85-4
ATC code	?
PubChem	3638
Chemical data
Formula	C₁₁H₁₃N O₃
Mol. mass	207.226
Pharmacokinetic data
Bioavailability	?
Metabolism	Hepatic
Half life	?
Excretion	Renal
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	?

Hydrastinine is a semisynthetic alkaloid from the hydrolysis of the alkaloid Hydrastine, which was found naturally in small quantites in Hydrastis canadensis L. (Ranunculaceae) Hydrastinine was produced by oxidative splitting of Hydrastine hydrochloride with nitric acid in good yield. The drug was patented by Bayer as a haemostatic drug during 1910s.

Category: Alkaloids