Host-guest chemistry

    In supramolecular chemistry, host-guest chemistry describes complexes that are composed of two or more molecules or ions held together in unique structural relationships by hydrogen bonding or by ion pairing or by Van der Waals force other than those of full covalent bonds.

Additional recommended knowledge

Essential Laboratory Skills Guide

Safe Weighing Range Ensures Accurate Results

Daily Sensitivity Test

The host component is defined as an organic molecule or ion whose binding sites converge in the complex and the guest component is defined as any molecule or ion whose binding sites diverge in the complex.

Common host molecules

• Cyclodextrins
• Calixarenes
• Cucurbiturils
• Porphyrins
• Crown ethers
• Zeolites
• Cryptophanes

Examples

Host-guest chemistry is observed in:

• Inclusion compounds
• Intercalation compounds
• Clathrates
• Cryptands
• Molecular tweezers

See also

• Molecular recognition