To use all functions of this page, please activate cookies in your browser.
my.chemeurope.com
With an accout for my.chemeurope.com you can always see everything at a glance – and you can configure your own website and individual newsletter.
- My watch list
- My saved searches
- My saved topics
- My newsletter
Hemetsberger indole synthesisThe Hemetsberger indole synthesis (also called the Hemetsberger-Knittel synthesis) is a chemical reaction that thermally decomposes a 3-aryl-2-azido-propenoic ester into an indole-2-carboxylic ester.[1][2] Additional recommended knowledgeYields are typically above 70%. However, this is not a popular reaction, due to the lack of stability and difficulty in synthesizing the starting material. Reaction mechanismThe mechanism is unknown. However, aziridine[3] intermediates have been isolated. The mechanism is postulated to proceed via a nitrene intermediate.[4] References
|
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Hemetsberger_indole_synthesis". A list of authors is available in Wikipedia. |