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HLA-DR10
HLA-DR10 (DR10) is a HLA-DR serotype that recognizes the DRB1*1001 gene product. Additional recommended knowledge
Serology
The serological reaction of DR10 is relatively good. Disease associationsBy serotpyeDR10 sertoype or cognate alleles are associated with: Lichen planus[2] By alleleDRB1*1001 is associated with ovarian cancer[3] and invasive squamous cell cervical cancer (SCC)[4] Extended linkageDRB1*1001:DQA1*01:DQB1*05 haplotype: Rheumatoid arthritis[5] The primary involvement appears to be DR10. Genetic Linkage
HLA-DR10 is not genetically linked to DR51, DR52 or DR53, but is linked to HLA-DQ1 and DQ5 serotypes. One haplotype found in caucasions is the HLA-A1-B37-Cw6-DR10-DQ5. References
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This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "HLA-DR10". A list of authors is available in Wikipedia. |