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HLA-DMHLA-DM is an intracellular protein involved in peptide presentation by MHC class II. It is encoded by the genes HLA-DMA and HLA-DMB. HLA-DM functions by promoting the dissociation of the CLIP peptide (a place holder peptide) from MHC class II, and stabilizes MHC class II allowing exogenous peptides to bind. |
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "HLA-DM". A list of authors is available in Wikipedia. |