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HLA-A11




major histocompatibility complex (human), class I, A11
Alleles	A1101 A1102 A1103 A1104
Structure (See HLA-A)
Identifiers	1101 1102 1103 1104
Symbol(s)	HLA-A
EBI-HLA	A*1101
EBI-HLA	A*1102
EBI-HLA	A*1103
EBI-HLA	A*1104
Shared data
Locus	chr.6 6p21.31

HLA-A11 (A11) is an HLA-A serotype. The serotype identifies the more common HLA-A*11 gene products. A11 is more common in eastern Asia particularly along the coastal regions of china.

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Serotype

A11 serotype recognition of Some HLA A*11 allele-group gene products^[1]
A*11	A11	A10	Sample
allele	%	%	size (N)
*1101	99		2530
*1102	76		42
*1103	83		18
*1104	60		6
*1105	66	33	3

Serotyping of A11 demonstrates better recognition of the *1101 gene products and poorer recognition of other A*11 gene products. Ther are ~40 recognized alleles of A*11. There is only one null classified as A11.

Disease Associations

By allele

A*1104 is associated with increased risk for cervical neoplasia resulting from human papillomavirus infection^[2]

A11-B Haplotypes

A11-B13

A11-Cw2-B13 (Li)
A11-Cw9-B13 (Southern China & SE Asia)
A11-C10-B13 Buyi
A11-CBL-B13 Northern China

References

^ derived from IMGT/HLA
^ Chan D, Cheung T, Tam A, Cheung J, Yim S, Lo K, Siu N, Zhou D, Chan P (2005). "Risk association between human leukocyte antigen-A allele and high-risk human papillomavirus infection for cervical neoplasia in Chinese women.". J Infect Dis 192 (10): 1749-56. PMID 16235173.

v • d • e HLA-A Serotypes
HLA-A - A1 - A2 - A3 - A9 (A23 - A24) - A10 (A25 - A26 - A34 - A43 - A66) - A11 - A19 (A29 - A30 - A31 - A32 - A33 - A74) - A28 (A68 - A69) - A36 - A80

Category: HLA-A alleles

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "HLA-A11". A list of authors is available in Wikipedia.

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