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Grepafloxacin



Grepafloxacin
Systematic (IUPAC) name
1-cyclopropyl-6-fluoro-5-methyl-7-(3-methylpiperazin-1-yl)- 4-oxo-quinoline- 3-carboxylic acid
Identifiers
CAS number 119914-60-2
ATC code J01MA11
PubChem 72474
DrugBank APRD01003
Chemical data
Formula C19H22FN3O3 
Mol. mass 359.395 g/mol
Pharmacokinetic data
Bioavailability  ?
Protein binding 50%
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

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Legal status
Routes  ?

Grepafloxacin hydrochloride (Raxar®, Glaxo Wellcome) is an oral broad-spectrum quinoline antibacterial agent used to treat bacterial infections. Grepafloxacin was withdrawn in the United States due to its side effect of lengthening the QT interval on the electrocardiogram, leading to cardiac events and sudden death.

 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Grepafloxacin". A list of authors is available in Wikipedia.
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