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Girisopam


Girisopam
Systematic (IUPAC) name
1-(3-chlorophenyl)-7,8-dimethoxy-4-methyl-5H-2,3-benzodiazepine
Identifiers
CAS number	82230-53-3
ATC code	?
PubChem	71257
Chemical data
Formula	C₁₈H₁₇Cl N₂O₂
Mol. mass	328.79
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	?

Girisopam (GYKI-51189) is a drug which is a 2,3-benzodiazepine derivative, related to tofisopam. It has selective anxiolytic action with no sedative, anticonvulsant or muscle relaxant effects.^[1]^[2]^[3]

References

^ Andrási F, Horváth K, Sineger E, Berzsenyi P, Borsy J, Kenessey A, Tarr M, Láng T, Kórösi J, Hámori T. Neuropharmacology of a new psychotropic 2,3-benzodiazepine. Arzneimittelforschung. 1987 Oct;37(10):1119-24.
^ Horváth K, Andrási F, Botka P, Hámori T. Anxiolytic profile of girisopam and GYKI 52,322 (EGIS 6775). Comparison with chlordiazepoxide and buspirone. Acta Physiologica Hungarica. 1992;79(2):153-61.
^ Horváth EJ, Salamon C, Bakonyi A, Fekete MI, Palkovits M. [(3)H]-girisopam, a novel selective benzodiazepine for the 2, 3-benzodiazepine binding site. Brain Research. Brain Research Protocols. 1999 Jul;4(2):230-5.

[1]

v • d • e Benzodiazepines (N05BA, N05CD)
1,4-Benzodiazepines	Bromazepam • Camazepam • Chlordiazepoxide • Cinolazepam • Clonazepam • Clorazepate • Cyprazepam • Delorazepam • Diazepam • Doxefazepam • Elfazepam • Ethyl loflazepate • Fletazepam • Fludiazepam • Fosazepam • Flunitrazepam • Flurazepam • Flutoprazepam • Gidazepam • Halazepam • Iclazepam • Lorazepam • Lormetazepam • Meclonazepam • Medazepam • Menitrazepam • Metaclazepam • Nimetazepam • Nitrazepam • Nordazepam • Oxazepam • Phenazepam • Pinazepam • Pivoxazepam • Prazepam • Quazepam • QH-II-66 • Reclazepam • Sulazepam • Temazepam • Tetrazepam • Uldazepam
Triazolobenzodiazepines	Adinazolam • Alprazolam • Estazolam • Triazolam • Zapizolam
Imidazobenzodiazepines	Bretazenil • Flumazenil • Imidazenil • Loprazolam • Midazolam • Ro15-4513
Oxazolobenzodiazepines	Cloxazolam • Flutazolam • Haloxazolam • Mexazolam • Oxazolam
Thienobenzodiazepines	Brotizolam • Clotiazepam • Etizolam
1,5-Benzodiazepines	Arfendazam • Clobazam • Lofendazam • Triflubazam
2,3-Benzodiazepines	Girisopam • GYKI-52895 • Nerisopam • Tofisopam
Benzodiazepine Prodrugs	Avizafone • Rilmazafone
Others	Bentazepam • Ketazolam • Tifluadom • Zolazepam

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Girisopam". A list of authors is available in Wikipedia.