Gilbert Chu

Gilbert Chu (朱著文) is an American Professor of Biochemistry and Medicine at Stanford University.

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He received a B.A. in Physics from Princeton University in 1967, a Ph.D in Physics from M.I.T. in 1973. a M.D from Harvard Medical School in 1980. He joined the Stanford faculty in 1987 as Professor of Biochemistry, and as a practicing physician in the Division of Oncology at the Stanford Medical School. His research has involved how cells react to DNA damage from radiation. His research in cancer treatment has involved developing electroporation techniques to use with microarrays to study transcriptional responses to DNA damage in cancer patients.

He was one of three developers of instrumentation and mathematical programs for data analysis.[1] He has the Clinical Scientist Award for Translational Research from Burroughs-Wellcome Fund (Wellcome Trust), from the Rita Allen Foundation, and from the Mary Kay Ash charitable Foundation.

His younger brother Steven Chu is a Nobel laureate.^[1] His other younger brother is the attorney Morgan Chu.

Selected publications

• Tusher V, Tibshirani R, Chu G "Significance analysis of microarrays applied to the ionizing radiation response" Proceedings of the National Academy of Sciences Proc. Natl. Acad. Sci. USA Apr 24, 2001; 98: 5116-5121. Times Cited: 2902

• Chu G, Hayakawa H, Berg P "Electroporation For The Efficient Transfection Of Mammalian-Cells With DNA" Nucleic Acids Research 15 (3): 1311-1326 Feb 11 1987 Times Cited: 697

• Chu G, "Cellular-Responses To Cisplatin - The Roles Of Dna-Binding Proteins And Dna-Repair" Journal Of Biological Chemistry 269 (2): 787-790 Jan 14 1994 Times Cited: 393

• Chu G "Double Strand Break Repair" Journal Of Biological Chemistry 272 (39): 24097-24100 Sep 26 1997 Times Cited: 155

• Tang Jy, Hwang Bj, Ford Jm, et al. "Xeroderma Pigmentosum P48 Gene Enhances Global Genomic Repair And Suppresses Uv-Induced Mutagenesis" Molecular Cell 5 (4): 737-744 Apr 2000 Times Cited: 137

• Rathmell Wk, Chu G, "A Dna End-Binding Factor Involved In Double-Strand Break Repair And V(D)J Recombination " Molecular And Cellular Biology 14 (7): 4741-4748 Jul 1994 Times Cited: 135

• Errami A, Smider V, Rathmell WK, et al., "Ku86 defines the genetic defect and restores X-ray resistance and V(D)J recombination to complementation group 5 hamster cell mutants" Molecular And Cellular Biology 16 (4): 1519-1526 Apr 1996 Times Cited: 112

A complete listing of publications can be found here.

References