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Gestodene


Gestodene
Systematic (IUPAC) name
(17S)-13-ethyl-17-ethynyl-17-hydroxy-1,2,6,7,8,9, 10,11,12,14-decahydrocyclopenta[a]phenanthren-3-one
Identifiers
CAS number	60282-87-3
ATC code	G03AA10
PubChem	43249
Chemical data
Formula	C₂₁H₂₆O₂
Mol. mass	310.430 g/mol
Pharmacokinetic data
Bioavailability	in vitro 99% using ³H=R5020 / in vivo similar to progesterone
Metabolism	?
Half life	16 to 18 hrs.
Excretion	urinary tract mainly
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	oral administration

Gestodene is a progestogen hormonal contraceptive.

v • d • e Sex hormones and related agents (primarily G03, also L02, H01C) - human endogenous in CAPS
Progestogens: (receptor)	PROGESTERONE, Desogestrel, Drospirenone, Dydrogesterone, Ethisterone, Etonogestrel, Ethynodiol diacetate, Gestodene, Gestonorone, Levonorgestrel, Lynestrenol, Medroxyprogesterone, Megestrol, Norelgestromin, Norethisterone, Norethynodrel, Norgestimate, Norgestrel, Norgestrienone, Tibolone Selective progesterone receptor modulator: Asoprisnil, CDB-4124 Antiprogestogen: Mifepristone
Androgens: (receptor)	TESTOSTERONE, Androstanolone, Fluoxymesterone, Mesterolone, Methyltestosterone, (see also anabolic steroids) Antiandrogens: Bicalutamide, Cyproterone, Flutamide, Nilutamide, Spironolactone
Estrogens: (receptor)	ESTRADIOL, ESTRIOL, ESTRONE, Chlorotrianisene, Dienestrol, Diethylstilbestrol, Ethinylestradiol, Fosfestrol, Mestranol, Polyestradiol phosphate Selective estrogen receptor modulator: Bazedoxifene, Clomifene, Fulvestrant, Lasofoxifene, Raloxifene, Tamoxifen, Toremifene Aromatase inhibitor: Aminogluthetimide, Anastrozole, Exemestane, Formestane, Letrozole, Vorozole
Gonadotropins: (FSHR/LHCGR)	ovulation stim.: Clomifene, Urofollitropin Antigonadotropins: Danazol, Gestrinone
GnRH: (receptor)	agonist: Buserelin, Goserelin, Histrelin, Leuprorelin, Nafarelin, Triptorelin antagonist: Abarelix, Cetrorelix, Ganirelix