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Gattermann reaction

The Gattermann rection, named for the German chemist Ludwig Gattermann, in organic chemistry refers to a reaction of hydrocyanic acid with an aromatic compound, in this case benzene, under catalysis with Friedel-Crafts catalyst (aluminium chloride).^[1] The reaction is similar to the Friedel-Crafts reaction

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It should not confused with the reaction where a diazonium salt is converted to an aryl halide by using copper powder and hydrochloric acid as opposed to using cuprous salt of the halide as in the Sandmeyer reaction.^[2] Although in some articles and books this reaction is also called Gatterman reaction.^[3]

References

^ L. Gattermann, W. Berchelmann (1898). "Synthese aromatischer Oxyaldehyde". Berichte der deutschen chemischen Gesellschaft 31 (2): 1765-1769. doi:10.1002/cber.18980310281.
^ L. Gattermann (1890). "Untersuchungen über Diazoverbindungen". Berichte der deutschen chemischen Gesellschaft 23 (1): 1218-1228. doi:10.1002/cber.189002301199.
^ R. N. Morrison, R. T. Boyd. Organic Chemistry, 869.