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Fructose 6-phosphate
Fructose 6-phosphate (also known as the Neuberg ester) is fructose sugar phosphorylated on carbon 6 (ie. is a fructosephosphate). The β-D-form of this compound is very common in cells. The vast majority of glucose and fructose entering a cell will become converted to this at some point. The name Neuberg ester comes from the German biochemist Carl Neuberg. Additional recommended knowledge
HistoryIn 1918, Carl Neuberg found that the compound (only later identified as fructose 6-phosphate) could be produced by mild acid hydrolysis of "Harden-Young ester" (fructose 2,6-bisphosphate).[1] Fructose 6-phosphate in glycolysisFructose 6-phosphate lies within the glycolysis metabolic pathway and is produced by isomerisation of glucose 6-phosphate. It is in turn further phosphorylated to fructose-1,6-bisphosphate.
Compound C00668 at KEGG Pathway Database. Enzyme 5.3.1.9 at KEGG Pathway Database. Compound C05345 at KEGG Pathway Database. Enzyme 2.7.1.11 at KEGG Pathway Database. Enzyme 3.1.3.11 at KEGG Pathway Database. Reaction [1] at KEGG Pathway Database. Compound C05378 at KEGG Pathway Database. Fructose 6-phosphate isomerismFructose 6-phosphate has only one biologically active isomer, the β-D-form. There are many other isomers, analogous to those of fructose. See also
References
Categories: Glycolysis | Organophosphates |
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This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Fructose_6-phosphate". A list of authors is available in Wikipedia. |