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Fluocortolone
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Systematic (IUPAC) name
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(6S,8S,9R,10S,11S,13S,14S,16R,17S)- 6-fluoro-11-hydroxy-17-(2-hydroxyacetyl)- 10,13,16-trimethyl-6,7,8,9,11,12,14,15,16,17- decahydrocyclopenta[a]phenanthren-3-one
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Identifiers
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CAS number
| 152-97-6
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ATC code
| C05AA08 D07AC05 H02AB03
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PubChem
| 9053
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Chemical data
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Formula | C22H29FO4
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Mol. mass | 376.462 g/mol
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Pharmacokinetic data
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Bioavailability | ?
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Metabolism | ?
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Half life | ?
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Excretion | ?
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Therapeutic considerations
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Pregnancy cat.
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?
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Legal status
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Routes
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Fluocortolone is a glucocorticoid used in the treatment of several conditions, including hemorrhoids.
Corticosteroids - glucocorticoid/receptor and mineralocorticoid/receptor (A07EA, C05AA, D07, D10AA, H02, R01AD, R03BA, S01BA, S02B, and S03B) |
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Endogenous | Aldosterone, Cortisone, Hydrocortisone/cortisol, Desoxycortone |
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Others | Alclometasone, Amcinonide, Beclometasone, Betamethasone, Budesonide, Ciclesonide, Clobetasol, Clobetasone, Clocortolone, Cloprednol, Cortivazol, Deflazacort, Deoxycorticosterone, Desonide, Desoximetasone, Dexamethasone, Diflorasone, Diflucortolone, Difluprednate, Fluclorolone, Fludrocortisone, Fludroxycortide, Flumetasone, Flunisolide, Fluocinolone acetonide, Fluocinonide, Fluocortin, Fluocortolone, Fluorometholone, Fluperolone, Fluprednidene, Fluticasone, Formocortal, Halcinonide, Halometasone, Hydrocortisone aceponate, Hydrocortisone buteprate, Hydrocortisone butyrate, Loteprednol, Medrysone, Meprednisone, Methylprednisolone,Methylprednisolone aceponate, Mometasone furoate, Paramethasone, Prednicarbate, Prednisone, Prednisolone, Prednylidene, Rimexolone, Tixocortol, Triamcinolone, Ulobetasol |
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Vasoprotectives (C05) |
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Antihemorrhoidals for topical use | corticosteroids (Hydrocortisone, Prednisolone, Betamethasone, Fluorometholone, Fluocortolone, Dexamethasone, Fluocinolone acetonide, Fluocinonide) - local anesthetics (Lidocaine, Tetracaine, Benzocaine, Cinchocaine, Procaine, Oxetacaine, Pramocaine) - other (Tribenoside) |
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Antivaricose therapy | heparins or heparinoids for topical use (Organo-heparinoid, Sodium apolate, Heparin, Pentosan polysulfate) - sclerosing agents for local injection (Monoethanolamine oleate, Polidocanol, Invert sugar, Sodium tetradecyl sulfate, Phenol) - Other (Calcium dobesilate) |
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Capillary stabilising agents | bioflavonoids (Rutoside, Monoxerutin, Diosmin, Troxerutin, Hidrosmin) - other (Tribenoside) |
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Additional recommended knowledge
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