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Flunisolide



Flunisolide
Systematic (IUPAC) name
6α-Fluoro-11β,16α,17,21- tetrahydroxypregna-1,4- diene-3,20-dione cyclic 16,17-acetal acetone
Identifiers
CAS number 3385-03-3
ATC code R01AD04 R03BA03
PubChem 82153
DrugBank APRD00976
Chemical data
Formula C24H31FO6 
Mol. mass 434.498 g/mol
Pharmacokinetic data
Bioavailability  ?
Protein binding 40% after oral inhalation
Metabolism  ?
Half life 1.8 hours
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?

Legal status
Routes Inhaled

Flunisolide (marketed as AeroBid, Nasalide, Nasarel) is a corticosteroid often prescribed as treatment for allergic rhinitis.

The principal mechanism of action of flunisolide is to activate glucocorticoid receptors. It also has anti-inflammatory action.


v • d • e
Corticosteroids - glucocorticoid/receptor and mineralocorticoid/receptor
(A07EA, C05AA, D07, D10AA, H02, R01AD, R03BA, S01BA, S02B, and S03B)
EndogenousAldosterone, Cortisone, Hydrocortisone/cortisol, Desoxycortone
OthersAlclometasone, Amcinonide, Beclometasone, Betamethasone, Budesonide, Ciclesonide, Clobetasol, Clobetasone, Clocortolone, Cloprednol, Cortivazol, Deflazacort, Deoxycorticosterone, Desonide, Desoximetasone, Dexamethasone, Diflorasone, Diflucortolone, Difluprednate, Fluclorolone, Fludrocortisone, Fludroxycortide, Flumetasone, Flunisolide, Fluocinolone acetonide, Fluocinonide, Fluocortin, Fluocortolone, Fluorometholone, Fluperolone, Fluprednidene, Fluticasone, Formocortal, Halcinonide, Halometasone, Hydrocortisone aceponate, Hydrocortisone buteprate, Hydrocortisone butyrate, Loteprednol, Medrysone, Meprednisone, Methylprednisolone,Methylprednisolone aceponate, Mometasone furoate, Paramethasone, Prednicarbate, Prednisone, Prednisolone, Prednylidene, Rimexolone, Tixocortol, Triamcinolone, Ulobetasol
v • d • e
Decongestants and other nasal preparations (R01)
Topical: sympathomimetics, plainCyclopentamine - Ephedrine - Phenylephrine - Oxymetazoline - Tetryzoline - Xylometazoline - Naphazoline - Tramazoline - Metizoline - Tuaminoheptane - Fenoxazoline - Tymazoline - Epinephrine
Topical: antiallergic agents, excluding corticosteroidsCromoglicic acid - Levocabastine - Azelastine - Antazoline - Spaglumic acid - Thonzylamine - Nedocromil - Olopatadine
Topical: corticosteroidsBeclometasone - Prednisolone - Dexamethasone - Flunisolide - Budesonide - Betamethasone - Tixocortol - Fluticasone - Mometasone furoate - Triamcinolone
Topical: other nasal preparationsCalcium hexamine thiocyanate - Retinol - Ipratropium bromide - Ritiometan - Mupirocin - Hexamidine - Framycetin
Systemic use: SympathomimeticsPhenylpropanolamine - Pseudoephedrine - Phenylephrine
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Flunisolide". A list of authors is available in Wikipedia.
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