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Flumetasone
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Systematic (IUPAC) name
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(6S,8S,9S,10S,11S,13S,14S,16R,17R)-6,9-difluoro- 11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16- trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a] phenanthren-3-one
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Identifiers
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CAS number
| 2135-17-3
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ATC code
| D07AB03 D07XB01
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PubChem
| 16490
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Chemical data
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Formula | C22H28F2O5
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Mol. mass | 410.452 g/mol
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Pharmacokinetic data
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Bioavailability | ?
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Metabolism | Hepatic, CYP3A4-mediated
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Half life | ?
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Excretion | ?
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Therapeutic considerations
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Pregnancy cat.
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?
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Legal status
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Routes
| Topical
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Flumetasone (usually as the pivalic acid ester flumetasone pivalate, trade name Locacorten) is a corticosteroid for topical use. It is available in combination with clioquinol, under the trade name Locacorten-Vioform, for the treatment of otitis externa and otomycosis.
Corticosteroids - glucocorticoid/receptor and mineralocorticoid/receptor (A07EA, C05AA, D07, D10AA, H02, R01AD, R03BA, S01BA, S02B, and S03B) |
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Endogenous | Aldosterone, Cortisone, Hydrocortisone/cortisol, Desoxycortone |
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Others | Alclometasone, Amcinonide, Beclometasone, Betamethasone, Budesonide, Ciclesonide, Clobetasol, Clobetasone, Clocortolone, Cloprednol, Cortivazol, Deflazacort, Deoxycorticosterone, Desonide, Desoximetasone, Dexamethasone, Diflorasone, Diflucortolone, Difluprednate, Fluclorolone, Fludrocortisone, Fludroxycortide, Flumetasone, Flunisolide, Fluocinolone acetonide, Fluocinonide, Fluocortin, Fluocortolone, Fluorometholone, Fluperolone, Fluprednidene, Fluticasone, Formocortal, Halcinonide, Halometasone, Hydrocortisone aceponate, Hydrocortisone buteprate, Hydrocortisone butyrate, Loteprednol, Medrysone, Meprednisone, Methylprednisolone,Methylprednisolone aceponate, Mometasone furoate, Paramethasone, Prednicarbate, Prednisone, Prednisolone, Prednylidene, Rimexolone, Tixocortol, Triamcinolone, Ulobetasol |
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Additional recommended knowledge
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