Ethylenediamine dihydroiodide

Ethylenediamine dihydroiodide (EDDI) is a water-soluble salt of ethylenediamine and hydrogen iodide. It is a colorless to light yellow crystalline powder. Its chemical formula is C₂H₆N₂.2HI. It is nonflammable, but iodine may be released during a fire.

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EDDI is used as a pet food additive and cattle feed additive with high bioavailability. It is used to prevent iodine deficiency. The United States Food and Drug Administration suggests a limit of intake to 50 mg/head/day.^[1] Although EDDI is generally recognized as safe (GRAS) only as a nutrient source of iodine, administration of EDDI also has preventative effects on foot rot in cattle.^[2]

EDDI may react with sulfates and release free iodine.^{[citation needed]} Other iodine supplements in animal feed are calcium iodate (most stable) and potassium iodide (most water-soluble, least stable).

References

1. ^ The Elimination of Iodine Deficiency Disorders, A Resource Package for Central and Eastern Europe, the Commonwealth of Independent States and Baltic States
2. ^ Berg JN, Maas JP, Paterson JA, Krause GF, Davis LE (1984). "Efficacy of ethylenediamine dihydriodide as an agent to prevent experimentally induced bovine foot rot". Am. J. Vet. Res. 45 (6): 1073–8. PMID 6146277.