My watch list

Epoxide hydrolase

epoxide hydrolase 1, microsomal (xenobiotic)
Identifiers
Symbol	EPHX1
Alt. Symbols	EPHX
Entrez	2052
HUGO	3401
OMIM	132810
RefSeq	NM_000120
UniProt	P07099
Other data
EC number	3.3.2.3
Locus	Chr. 1 q42.1

epoxide hydrolase 2, cytoplasmic
Identifiers
Symbol	EPHX2
Entrez	2053
HUGO	3402
OMIM	132811
RefSeq	NM_001979
UniProt	P34913
Other data
Locus	Chr. 8 p21

Epoxide hydrolase (also known as Epoxide hydratase) functions in detoxication during drug metabolism. It converts epoxides from the degradation of aromatic compounds to trans-dihydrodiols which can be conjugated and excreted from the body.

Additional recommended knowledge

What is the Sensitivity of my Balance?

Better weighing performance in 6 easy steps

Correct Test Weight Handling Guide: 12 Practical Tips

Epoxides are significant as cytochrome P450 oxidase metabolites of unsaturated carbon-carbon bonds, but are also mutagenic. Epoxide hydrolase is present in large quantity on endoplasmic reticulum.