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Epinastine


Epinastine
Systematic (IUPAC) name
3-amino-9,13b-dihydro-1H- dibenz(c,f)imidazo(1,5-a)azepine
Identifiers
CAS number	80012-43-7
ATC code	R06AX24 S01GX10
PubChem	3241
DrugBank	APRD00043
Chemical data
Formula	C₁₆H₁₅N₃
Mol. mass	249.311 g/mol
Pharmacokinetic data
Bioavailability	?
Protein binding	64%
Metabolism	?
Half life	12 hours
Excretion	?
Therapeutic considerations
Pregnancy cat.	C
Legal status
Routes	Eye drops

Epinastine hydrochloride (Elestat) is an antihistamine that is used in eye drops to treat allergic conjunctivitis. Elestat is presently marketed by Allergan.

v • d • e Antihistamines (primarily R06)
Aminoalkyl ethers	Bromazine • Carbinoxamine • Clemastine • Chlorphenoxamine • Diphenylpyraline • Diphenhydramine • Doxylamine • Orphenadrine • Phenyltoloxamine
Substituted alkylamines	Brompheniramine • Chlorphenamine • Dexbrompheniramine • Dexchlorpheniramine • Dimetindene • Pheniramine • Talastine
Substituted ethylenediamines	Chloropyramine • Histapyrrodine • Mepyramine • Methapyrilene • Tripelennamine (Pyribenzamine)
Phenothiazine derivatives	Alimemazine • Hydroxyethylpromethazine • Isothipendyl • Mequitazine • Methdilazine • Oxomemazine • Promethazine
Piperazine derivatives	Buclizine • Cetirizine • Chlorcyclizine • Cinnarizine • Cyclizine • Hydroxyzine • Levocetirizine • Meclizine • Niaprazine • Oxatomide
Others for systemic use	Antazoline • Azatadine • Bamipine • Cyproheptadine • Deptropine • Dimebon • Ebastine • Epinastine • Ketotifen • Mebhydrolin • Mizolastine • Phenindamine • Pimethixene • Pyrrobutamine • Rupatadine • Triprolidine • selective (Acrivastine • Astemizole • Azelastine • Desloratadine • Fexofenadine • Loratadine • Terfenadine)
For topical use	Bamipine • Chloropyramine • Chlorphenoxamine • Clemastine • Dimetindene • Diphenhydramine • Isothipendyl • Mepyramine • Promethazine • Thenalidine
Antiallergic agents excluding corticosteroids	Antazoline • Azelastine
Other antiallergics	Emedastine • Epinastine • Ketotifen • Olopatadine