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Emde degradationThe Emde degradation (also called Emde-reaction or Emde-reduction) is a method for the reduction of a quaternary ammonium cation to a tertiary amine with sodium amalgam [1] [2] [3] Additional recommended knowledgeThis organic reaction was first described in 1909 by the German chemist Hermann Emde and was for a long time of great importance in structure elucidation of many alkaloids, for example that of ephedrine. Alternative reducing agents exist for this reaction; for instance, lithium aluminum hydride. See also
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This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Emde_degradation". A list of authors is available in Wikipedia. |