Drostanolone propionate


Drostanolone propionate
Systematic (IUPAC) name
(2R,5S,8R,9S,10S,13S,14S,17S)-17-hydroxy-2,10,13-trimethyl-1,2,4,5,6,7,8,9, 11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one
Identifiers
CAS number	58-19-5
ATC code	A14
PubChem	6011
Chemical data
Formula	C₂₃H₃₆O₃
Mol. mass	360.53 g/mol
SMILES	search in eMolecules, PubChem
Pharmacokinetic data
Bioavailability	Oral 0-2%, Intramuscular 100%
Protein binding	highly
Metabolism	hepatic
Half life	?
Excretion	renal
Therapeutic considerations
Pregnancy cat.	X
Legal status	Schedule IV(CA) Schedule III(US)
Routes	Intramuscular injection or transdermal cream

Drostanolone (trade name Masteron) is an anabolic/androgenic steroid. It is known to be highly androgenic and mildly anabolic. It is incapable of aromatization and has similar properties to dihydrotestosterone. It has been successfully used as a breast cancer drug but because of the high risk of virilization safer options are prescribed.

Additional recommended knowledge

How to ensure accurate weighing results every day?

Guide to balance cleaning: 8 simple steps

Correct Test Weight Handling Guide: 12 Practical Tips

Use in sports

Masteron is used primarily by athletes who need to retain strength while losing mass. It is beneficial to runners and athletes who must remain in a certain weight class. It has gained popularity in the bodybuilding community as a diuretic and muscle defining drug.

Trivia

Ultimate Fighting Championship athlete Hermes Franca tested positive for use of Drostanolone following his July 7th 2007 lightweight championship bout against title holder Sean Sherk.

References

http://www.mmaweekly.com/absolutenm/templates/dailynews.asp?articleid=4359&zoneid=13 See it was Sherk

Eur J Cancer Clin Oncol. 1983 Sep;19(9):1231-7.
Cancer Res. 1982 Nov;42(11):4408-12 Marin P, Oden B, and Bjorntorp P. Assimilation and mobilization of triglycerides in subcutaneous abdominal and femoral adipose tissue in vivo in men: effects of androgens. J Clin Endocrinol Metab 80: 239-243, 1995
Sem Hop. 1982 Sep 23;58(34):1919-23.

v • d • e

Anabolic steroids (A14) (trademark names in brackets)

Androstan (carbon 19 present)