Dirlotapide

Dirlotapide is a drug used to treat obesity in dogs. It is manufactured by Pfizer and marketed as Slentrol.

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It works as a selective microsomal triglyceride transfer protein inhibitor. This blocks the assembly and release of lipoproteins into the bloodstream, thereby reducing fat absorption. It also elicits a satiety signal from lipid-filled cells lining the intestine.

It is supplied as an oral solution. It is not intended for use in humans or cats.

On January 5 2007, the FDA approved Slentrol, the first time the FDA has approved a drug for obese dogs.^[1]

References

1. ^ FDA approves 1st drug for obese dogs. Yahoo. Retrieved on 2007-01-06.