Diatrizoic acid

Diatrizoic acid (or its anionic form, Diatrizoate), also known as amidotrizoic acid, or 3,5-Diacetamido-2,4,6-triiodobenzoic acid, is an iodine-containing radiocontrast agent. It is also used to kill tapeworms.

Additional recommended knowledge

Daily Sensitivity Test

Essential Laboratory Skills Guide

Don't let static charges disrupt your weighing accuracy

Diatrizoate is considered a high-osmolality contrast agent. Its osmolality ranges from approximately 1500 mOsm/kg (50% solution)^[1] to over 2000 mOsm/kg (76% solution).^[2]

Administration

• It is given intravenously (under brand name Hypaque®, GE Healthcare) to enhance contrast in computed tomography, to image the kidneys and related structures, and to image blood vessels.
• It is given orally or by enema (Gastrografin®, Gastrovist®, Gastrovision®, MD-Gastroview®) to image the gastrointestinal tract.
• It is given by Foley catheter (Cystografin®) to image the urinary tract

Contraindications

A history of sensitivity to iodine is not a contraindication to using diatrizoate, although it suggests caution in use of the agent.

References

1. ^ Amersham Health (April 2006). Hypaque sodium (Diatrizoate Sodium) injection, solution. Product label. DailyMed. U.S. National Library of Medicine. Retrieved on 2007-03-29.
2. ^ Amersham Health (April 2006). Hypaque (Diatrizoate Meglumine and Diatrizoate Sodium) injection, solution. Product label. DailyMed. U.S. National Library of Medicine. Retrieved on 2007-03-29.