To use all functions of this page, please activate cookies in your browser.
my.chemeurope.com
With an accout for my.chemeurope.com you can always see everything at a glance – and you can configure your own website and individual newsletter.
- My watch list
- My saved searches
- My saved topics
- My newsletter
Desoxycorticosterone
Desoxycorticosterone (11-deoxycorticosterone) is a mineralocorticoid secreted from Zona reticularis and Zona fasciculata of the adrenal gland. In the cytosol of the mitochondrion, pregnenolone is converted to either androgens or 11-deoxycorticosterone and 11-deoxycortisol by enzymes of the endoplasmic reticulum. Then, 11-deoxycorticosterone, along with 11-deoxycortisol, re-enters the mitochondrion, where the enzymes are located for tissue-specific conversion to mineralocorticoids or glucocorticoids, respectively. Additional recommended knowledgeDesoxycorticosterone is commonly found in two forms: the acetate salt (desoxycorticosterone acetate, or DOCA) and the pivalate salt (desoxycorticosterone pivalate). Both forms are given as intramuscular injections as replacement therapy for Addison's disease. This disease is marked by insufficient adrenal function, including low mineralocorticoid levels. Desoxycorticosterone pivalate is sold for veterinary use by Novartis under the brand name Percoten. Referenceshttp://web.indstate.edu/thcme/mwking/steroid-hormones.html
|
||||||||||||||||||||||||||||||||||||||||||||||||
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Desoxycorticosterone". A list of authors is available in Wikipedia. |