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Clofoctol


Clofoctol
Systematic (IUPAC) name
2-[(2,4-dichlorophenyl)methyl]- 4-(2,4,4-trimethylpentan-2-yl)phenol
Identifiers
CAS number	37693-01-9
ATC code	J01XX03
PubChem	2799
Chemical data
Formula	C₂₁H₂₆Cl₂O
Mol. mass	365.336 g/mol
Pharmacokinetic data
Bioavailability	98%^[1]
Metabolism	Hepatic glucuronidation^[1]
Half life	?
Excretion	Biliary^[1]
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	Rectal (suppository)^[1]^[2]

Clofoctol is a bacteriostatic antibiotic. It is used in the treatment of respiratory tract and ear, nose and throat infections caused by Gram-positive bacteria.^[1]^[2]

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It is marketed in France under the trade name Octoplus and in Italy as Gramplus.

References

^ ^a ^b ^c ^d ^e Gramplus (Italian). Studio Medico Torrino (July 25 2007). Retrieved on 2007-08-10.
^ ^a ^b Clofoctol (French). BIAM (July 16 1999). Retrieved on 2007-08-10.

v • d • e Antibacterials for systemic use: others (J01X)
Glycopeptide	Vancomycin - Teicoplanin
Polymyxins	Colistin - Polymyxin B
Steroid antibacterials	Fusidic acid
Imidazole derivatives	Metronidazole - Tinidazole - Ornidazole
Nitrofuran derivatives	Nitrofurantoin - Nifurtoinol
Other	Fosfomycin - Xibornol - Clofoctol - Spectinomycin - Methenamine - Mandelic acid - Nitroxoline - Linezolid - Daptomycin - Hitachimycin - Dalbavancin - Telavancin