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Clobetasone
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Systematic (IUPAC) name
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(8S,9R,10S,13S,14S,16S,17R)-17-(2-Chloroacetyl)-9-fluoro-17-hydroxy-10,13,16-trimethyl-7,8,12,14,15,16-hexahydro-6H-cyclopenta[a]phenanthrene-3,11-dione
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Identifiers
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CAS number
| 54063-32-0
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ATC code
| D07AB01 S01BA09
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PubChem
| 71387
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Chemical data
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Formula | C22H26ClFO4
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Mol. mass | 408.891
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Pharmacokinetic data
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Bioavailability | ?
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Metabolism | ?
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Half life | ?
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Excretion | ?
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Therapeutic considerations
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Pregnancy cat.
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?
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Legal status
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Routes
| topical
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Clobetasone (INN[1]) is a corticosteroid used in dermatology, for treating such skin inflammation as seen in eczema and other forms of dermatitis, and ophthalmology.
Additional recommended knowledge
It is available as clobetasone butyrate under the brand name Eumovate[2] or Trimovate[3], both manufactured by GlaxoSmithKline.
References
- ^ United Nations Statistics Division - Classifications Registry - Alphabetical index for HS 2002 Entries starting with 'C' (page 310 of 422)
- ^ Eumovate cream/ointment, NetDoctor.co.uk
- ^ Trimovate cream, NetDoctor.co.uk
Corticosteroids - glucocorticoid/receptor and mineralocorticoid/receptor (A07EA, C05AA, D07, D10AA, H02, R01AD, R03BA, S01BA, S02B, and S03B) |
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Endogenous | Aldosterone, Cortisone, Hydrocortisone/cortisol, Desoxycortone |
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Others | Alclometasone, Amcinonide, Beclometasone, Betamethasone, Budesonide, Ciclesonide, Clobetasol, Clobetasone, Clocortolone, Cloprednol, Cortivazol, Deflazacort, Deoxycorticosterone, Desonide, Desoximetasone, Dexamethasone, Diflorasone, Diflucortolone, Difluprednate, Fluclorolone, Fludrocortisone, Fludroxycortide, Flumetasone, Flunisolide, Fluocinolone acetonide, Fluocinonide, Fluocortin, Fluocortolone, Fluorometholone, Fluperolone, Fluprednidene, Fluticasone, Formocortal, Halcinonide, Halometasone, Hydrocortisone aceponate, Hydrocortisone buteprate, Hydrocortisone butyrate, Loteprednol, Medrysone, Meprednisone, Methylprednisolone,Methylprednisolone aceponate, Mometasone furoate, Paramethasone, Prednicarbate, Prednisone, Prednisolone, Prednylidene, Rimexolone, Tixocortol, Triamcinolone, Ulobetasol |
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