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Ceftibuten


Ceftibuten
Systematic (IUPAC) name
(6R,7R)-7-([(Z)-2-(2-amino-1,3-thiazol-4-yl)-5-hydroxy-5-oxopent-2-enoyl]amino) -8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Identifiers
CAS number	97519-39-6
ATC code	?
PubChem	5282242
Chemical data
Formula	C₁₅H₁₄N₄O₆S₂
Mol. mass	410.427 g.mol^-1
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	?

Ceftibuten is a third-generation cephalosporin antibiotic. It is an orally-administered agent, with 2 dosage forms, capsule or oral suspension. It is marketed by Shionogi USA under the trade name Cedax®

Additional recommended knowledge

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Essential Laboratory Skills Guide

1 Clinical use
- 1.1 Indications
- 1.2 Formulations
2 See also

Clinical use

Main article: Cephalosporin

Indications

Ceftibuten is used to treat acute bacterial exacerbations of chronic bronchitis (ABECB), acute bacterial otitis media, pharyngitis, and tonsilitis.

Formulations

Ceftibuten is available as capsules containing 400 mg, and a powder for oral suspension containing 90 mg per 5 ml.

v • d • e Antibacterials for systemic use: beta-lactam antibiotics - cephalosporins and related (J01D)
First generation	Cefacetrile, Cefadroxil, Cefalexin, Cefaloglycin, Cefaloridine, Cefalotin, Cefapirin, Cefatrizine, Cefazedone, Cefazolin, Cefradine, Cefroxadine, Ceftezole
Second generation	Cefaclor, Cefamandole, Cefmetazole, Cefonicid, Ceforanide, Cefotiam, Cefprozil, Cefuroxime
Third generation	Cefdinir, Cefditoren, Cefetamet, Cefixime, Cefmenoxime, Cefodizime, Cefoperazone, Cefotaxime, Cefpiramide, Cefpodoxime, Cefsulodin, Ceftazidime, Ceftibuten, Ceftizoxime, Ceftriaxone, Latamoxef
Fourth generation	Cefepime, Cefpirome, Cefquinome
Other beta-lactam antibacterials	Monobactams (Aztreonam), Carbapenems (Meropenem, Ertapenem, Imipenem, Doripenem)