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Cefprozil


Cefprozil
Systematic (IUPAC) name
8-[2-amino-2-(4-hydroxyphenyl)-acetyl] amino-7-oxo-4-prop-1-enyl-2-thia-6- azabicyclo [ 4.2.0]oct-4-ene-5-carboxylic acid
Identifiers
CAS number	92665-29-7
ATC code	J01DC10
PubChem	5281006
DrugBank	APRD00461
Chemical data
Formula	C₁₈H₁₉N₃O₅S
Mol. mass	389.427 g/mol
Pharmacokinetic data
Bioavailability	?
Protein binding	36%
Metabolism	?
Half life	1.3 hours
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	?

Cefprozil, sometimes spelled cefproxil and sold under the brand name Cefzil, is a cephalosporin type antibiotic. In Europe, it is sold by the name Procef. It can be used to treat bronchitis, ear infections, skin infections, and other bacterial infections. It comes as a tablet and as a liquid suspension.

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Although there is a widely quoted cross-allergy risk of 10% between cephalosporins and penicillin, an article in the Journal of Family Practice (February 2006)^[1] has shown no increased risk for cross-allergy for cefprozil and several other 2nd generation or later cephalosporins.

References

^ http://www.jfponline.com/pdf%2F5502%2F5502JFP_AppliedEvidence1.pdf

v • d • e Antibacterials for systemic use: beta-lactam antibiotics - cephalosporins and related (J01D)
First generation	Cefacetrile, Cefadroxil, Cefalexin, Cefaloglycin, Cefaloridine, Cefalotin, Cefapirin, Cefatrizine, Cefazedone, Cefazolin, Cefradine, Cefroxadine, Ceftezole
Second generation	Cefaclor, Cefamandole, Cefmetazole, Cefonicid, Ceforanide, Cefotiam, Cefprozil, Cefuroxime
Third generation	Cefdinir, Cefditoren, Cefetamet, Cefixime, Cefmenoxime, Cefodizime, Cefoperazone, Cefotaxime, Cefpiramide, Cefpodoxime, Cefsulodin, Ceftazidime, Ceftibuten, Ceftizoxime, Ceftriaxone, Latamoxef
Fourth generation	Cefepime, Cefpirome, Cefquinome
Other beta-lactam antibacterials	Monobactams (Aztreonam), Carbapenems (Meropenem, Ertapenem, Imipenem, Doripenem)