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Mepivacaine


Mepivacaine
Systematic (IUPAC) name
N-(2,6-dimethylphenyl)- 1-methyl-piperidine-2-carboxamide
Identifiers
CAS number	96-88-8
ATC code	N01BB03
PubChem	4062
DrugBank	APRD01094
Chemical data
Formula	C₁₅H₂₂N₂O
Mol. mass	246.348 g/mol
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	C, use w/ caution, may cause fetal bradycardia
Legal status
Routes	?

Mepivacaine (pronounced /mɛˈpɪvəkeɪn/) is a local anesthetic of the amino amide type. Mepivacaine has a reasonably rapid onset (more rapid than that of procaine) and medium duration of action (shorter than that of procaine) and is marketed under various trade names including Carbocaine and Polocaine.

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Mepivacaine became available in the United States in the 1960s.

Mepivacaine is used in local infiltration and regional anesthesia. It is chemically related to bupivacaine but pharmacologically related to lidocaine. It is indicated for infiltration, nerve block, and epidural anesthesia. Mepivacaine is effective topically only in large doses and therefore should not be used by this route. (From AMA Drug Evaluations, 1994, p168)

v • d • e Anesthetics: Local anesthetics (N01B)
Esters of aminobenzoic acid	Procaine, Tetracaine, Chloroprocaine, Benzocaine
Amides	Bupivacaine, Lidocaine, Mepivacaine, Prilocaine, Cinchocaine, Etidocaine, Articaine, Ropivacaine, Levobupivacaine
Esters of benzoic acid	Cocaine
Other	Hexylcaine, Iontocaine, Lidocaine/prilocaine