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Carbarsone


Carbarsone
Systematic (IUPAC) name
[4-(carbamoylamino)phenyl]arsonic acid
Identifiers
CAS number	121-59-5
ATC code	??
PubChem	8480
Chemical data
Formula	C₇H₉As N₂O₄
Mol. mass	260.079 g/mol
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status	?
Routes	Oral

Carbarsone is an arsenic-based antiprotozoal drug which has been used in the treatment of amebiasis and other infections.^[1]^[2]^[3] It was available for use in the United States as a drug for amebiasis as late as 1991. Thereafter, it remained available as an additive for turkey feed for improving weight and controlling Blackhead disease.^[4]^[5]

References

^ SASAKI T, YOKAGAWA M, WYKOFF DE, RITICHIE LS (1956). "Asymptomatic amebiasis; treatment with atabrine in combination with carbarsone or chiniofon". United States Armed Forces medical journal 7 (3): 363–8. PMID 13299463.
^ RADKE RA (1955). "Ameboma of the intestine: an analysis of the disease as presented in 78 collected and 41 previously unreported cases". Ann. Intern. Med. 43 (5): 1048–66. PMID 13268997.
^ HOEKENGA MT (1951). "A comparison of aureomycin and carbarsone in the treatment of intestinal amebiasis". Am. J. Trop. Med. Hyg. 31 (4): 423–5. PMID 14857246.
^ McDougald LR (1979). "Efficacy and compatibility of amprolium and carbarsone against Coccidiosis and blackhead in turkeys". Poult. Sci. 58 (1): 76–80. PMID 572970.
^ Worden AN, Wood EC (1973). "The effect of Carbarsone (33.6 per cent w-v p-ureidobenzene arsonic acid) on bodyweight gain, food conversion and tissue arsenic levels of turkey poults". J. Sci. Food Agric. 24 (1): 35–41. PMID 4696593.