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Calgranulin



Calgranulin is an S-100 calcium-binding protein that is expressed in multiple cell types, including renal epithelial cells and neutrophils. Some in vitro evidence suggests that calgranulin can inhibit the precipitation of calcium oxalate in a urine-like environment at calgranulin concentrations below physiological concentrations.[1] Thus, it may also function in vivo as an inhibitor of calcium oxalate kidney stone formation. However, the role of calgranulin in the stone formation process has not been evaluated.

Genes

  • S100A8, S100A9, S100A12

References

  1. ^ Pillay S, Asplin J, Coe F (1998). "Evidence that calgranulin is produced by kidney cells and is an inhibitor of calcium oxalate crystallization". Am J Physiol 275 (2 Pt 2): F255-61. PMID 9691016.
v • d • e
Surface antigens
Histocompatibility/Human leukocyte antigenMHC - MHC class I (HLA-A, HLA-B, HLA-C, HLA-E)
MHC class II (HLA-DP, HLA-DQ, HLA-DR) - Minor histocompatibility antigen
OtherArrestin - Calgranulin - Blood group antigens - Cell adhesion molecules - Differentiation antigens
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Calgranulin". A list of authors is available in Wikipedia.
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