CCL1

Chemokine (C-C motif) ligand 1 (CCL1) is a small glycoprotein secreted by activated T cells that belongs to a family inflammatory cytokines known as chemokines. ^[1] CCL1 attracts monocytes, NK cells, and immature B cells and dendritic cells by interacting with a cell surface chemokine receptor called CCR8.^[2] This chemokine resides in a large cluster of CC chemokines on human chromosome 17.

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References

1. ^ Miller and Krangel. The Human Cytokine I-309 is a Monocyte Chemoattractant. Proceedings of the National Academy of Sciences, 1992, Vol 89, 2950-2954.
2. ^ Roos et al., Identification of CCR8, the receptor for the human CC chemokine I-309. J Biol Chem 1997 Vol 272, 17251–4.