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Butamirate


Butamirate
Systematic (IUPAC) name
2-(2-diethylaminoethoxy)ethyl 2-phenylbutanoate
Identifiers
CAS number	18109-80-3
ATC code	R05DB13
PubChem	28892
Chemical data
Formula	C₁₈H₂₉N O₃
Mol. mass	307.428 g/mol
Pharmacokinetic data
Bioavailability	?
Protein binding	98%
Metabolism	?
Half life	6 hours
Excretion	90% renal
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	?

Butamirate (or brospamin) is a non-opioid central cough suppressant. It acts on the cough center in the medulla oblongata. It does noc cause respiratory suppression, so should be safer than codeine.

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v • d • e Cough and cold preparations (R05)
Expectorants	Tyloxapol - Potassium iodide - Guaifenesin - Ipecacuanha - Althea root - Senega - Antimony pentasulfide - Creosote - Guaiacolsulfonate - Levoverbenone
Mucolytics	Acetylcysteine - Bromhexine - Carbocisteine - Eprazinone - Mesna - Ambroxol - Sobrerol - Domiodol - Letosteine - Stepronin - Tiopronin - Dornase alfa - Neltenexine - Erdosteine
Cough suppressants: Opium alkaloids and derivatives	Ethylmorphine - Hydrocodone - Codeine - Normethadone - Noscapine - Pholcodine - Dextromethorphan - Thebacon - Dimemorfan - Acetyldihydrocodeine - Zipeprol
Other cough suppressants	Benzonatate - Benproperine - Clobutinol - Isoaminile - Pentoxyverine - Oxolamine - Oxeladin - Clofedanol - Pipazetate - Bibenzonium bromide - Butamirate - Fedrilate - Dibunate - Droxypropine - Prenoxdiazine - Dropropizine - Cloperastine - Meprotixol - Piperidione - Tipepidine - Morclofone - Nepinalone - Levodropropizine - Dimethoxanate