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Bromazine


Bromazine
Systematic (IUPAC) name
2-[(4-bromophenyl)-phenylmethoxy]-N,N-dimethylethanamine
Identifiers
CAS number	118-23-0 1808-12-4 (hydrochloride)
ATC code	R06AA01
PubChem	2444
DrugBank	APRD00710
Chemical data
Formula	C₁₇H₂₀Br N O
Mol. mass	334.251 g/mol
Pharmacokinetic data
Bioavailability	High
Protein binding	96%
Metabolism	Mostly hepatic (CYP-mediated), also renal
Half life	1 to 4 hours
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	Oral

Bromazine (INN, also known as bromodiphenhydramine) is an antihistamine. It is a brominated derivative of diphenhydramine.

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v • d • e Antihistamines (primarily R06)
Aminoalkyl ethers	Bromazine • Carbinoxamine • Clemastine • Chlorphenoxamine • Diphenylpyraline • Diphenhydramine • Doxylamine • Orphenadrine • Phenyltoloxamine
Substituted alkylamines	Brompheniramine • Chlorphenamine • Dexbrompheniramine • Dexchlorpheniramine • Dimetindene • Pheniramine • Talastine
Substituted ethylenediamines	Chloropyramine • Histapyrrodine • Mepyramine • Methapyrilene • Tripelennamine (Pyribenzamine)
Phenothiazine derivatives	Alimemazine • Hydroxyethylpromethazine • Isothipendyl • Mequitazine • Methdilazine • Oxomemazine • Promethazine
Piperazine derivatives	Buclizine • Cetirizine • Chlorcyclizine • Cinnarizine • Cyclizine • Hydroxyzine • Levocetirizine • Meclizine • Niaprazine • Oxatomide
Others for systemic use	Antazoline • Azatadine • Bamipine • Cyproheptadine • Deptropine • Dimebon • Ebastine • Epinastine • Ketotifen • Mebhydrolin • Mizolastine • Phenindamine • Pimethixene • Pyrrobutamine • Rupatadine • Triprolidine • selective (Acrivastine • Astemizole • Azelastine • Desloratadine • Fexofenadine • Loratadine • Terfenadine)
For topical use	Bamipine • Chloropyramine • Chlorphenoxamine • Clemastine • Dimetindene • Diphenhydramine • Isothipendyl • Mepyramine • Promethazine • Thenalidine
Antiallergic agents excluding corticosteroids	Antazoline • Azelastine
Other antiallergics	Emedastine • Epinastine • Ketotifen • Olopatadine