My watch list
my.chemeurope.com  

my.chemeurope.com

With an accout for my.chemeurope.com you can always see everything at a glance – and you can configure your own website and individual newsletter.

  • My watch list
  • My saved searches
  • My saved topics
  • My newsletter
Register free of charge
Login  
eng  
DeutschEnglishFrançaisEspañol

Bromobimane



Bromobimane
Other names Bromobimane, mBBr
Identifiers
CAS number 71418-44-5
PubChem 24885999
Properties
Molecular formula C10H11BrN2O2
Molar mass 271.11
Melting point

152-154 °C

Solubility in water in MeOH, DMF, DMSO
Hazards
Main hazards alkylating agent
Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)
Infobox disclaimer and references

Bromobimane is a heterocyclic compound that is used as a reagent in biochemistry. It alkylates thiol groups, replacing the H with a fluorescent tag (λemission = 478 nm). Its alkylating properties are comparable to iodoacetamide.[1]

References

  1. ^ Paul C. Chinn, Vincent Pigiet, and Robert C. Fahey (1986). "Determination of thiol proteins using monobromobimane labeling and high-performance liquid chromatographic analysis: Application to Escherichia coli thioredoxin". Analytical Biochemistry 159: 143-149. doi:10.1016/0003-2697(86)90319-2.
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Bromobimane". A list of authors is available in Wikipedia.
Your browser is not current. Microsoft Internet Explorer 6.0 does not support some functions on Chemie.DE