Bodroux-Chichibabin aldehyde synthesis

The Bodroux-Chichibabin aldehyde synthesis is a chemical reaction whereby a Grignard reagent is converted to an aldehyde one carbon longer.

Additional recommended knowledge

Correct Test Weight Handling Guide: 12 Practical Tips

Weighing the right way

Guide to balance cleaning: 8 simple steps

Reaction of a Grignard reagent with triethyl orthoformate gives an acetal, which can be hydrolyzed to an aldehyde.

References

• Bodroux, F.; Compt. Rend. 1904, 138, 92.
• Chichibabin, A. E.; Ber. 1904,37, 186, 850.
• Smith, L. I. et al.; J. Org. Chem. 1941, 6, 437, 489.

See also

• Bouveault aldehyde synthesis