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Bis-HPPP

Bis-HPPP

IUPAC name	2,2-bis[4-(2,3-hydroxypropoxy)phenyl]propane
Identifiers
CAS number
SMILES	OCC(O)COc1ccc(cc1)C(C)(C)c2ccc(OCC(O)CO)cc2
Properties
Molecular formula	C₂₁H₂₈O₆
Molar mass	376.44 g/mol
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references

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2,2-Bis[4(2,3-hydroxypropoxy)phenyl]propane (bis-HPPP) is an organic compound structurally related to Bisphenol A.

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Together with methacrylic acid, bis-HPPP is released following the CE-catalyzed hydrolysis of 2,2-[4(2-hydroxy 3-methacryloxypropoxy)-phenyl]propane (bis-GMA). This reaction is very common in hydrolytic degradation of the dental resin since salivary esterases are able to cleave the ester bonds in acrylic polymers of dental composites.

Analysis by mass spectrometry demonstrated that hydrolytic reactions would cleave the ester bonds of both methacrylate units in bis-GMA and produce bis-HPPP along with two molecules of methacrylic acid.^[1]