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Barbexaclone


Barbexaclone
Systematic (IUPAC) name
(-)-N,α-Dimethylcyclohexaneethylammonium.5-ethyl-5-phenyl-barbiturate
Identifiers
CAS number	4388-82-3
ATC code	N03AA04
PubChem	71196
Chemical data
Formula	C₂₂H₃₃N₃O₃
Mol. mass	387.52 g/mol
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	?

Barbexaclone (marketed in Italy as Maliasin by Abbott Laboratories) is a salt compound of phenobarbital and propylhexedrine. It was introduced in 1983. It is reported to be as effective as phenobarbital but better tolerated. 100 mg of barbexaclone is equivalent to 60 mg of phenobarbital. It is not available on prescription in the UK or U.S.

Additional recommended knowledge

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References

The Treatment of Epilepsy 2nd Ed by S. D. Shorvon (Editor), David R. Fish (Editor), Emilio Perucca (Editor), W. Edwin Dodson (Editor). Published by Blackwell 2004. ISBN 0-632-06046-8

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Barbiturates (N01AF, N03AA, N05CA)

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