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AzoleAn azole is a class of five-membered nitrogen heterocyclic ring compounds containing at least one other noncarbon atom, nitrogen, sulfur or oxygen. The parent compounds are aromatic and have two double bonds; there are successively reduced analogs (azolines and azolidines) with less. Names of azoles maintain the prefix upon reduction (such as pyrazoline, pyrazolidine), except for pyrrole, which has no -azole suffix and is reduced to pyrroline and pyrrolidine. Additional recommended knowledgeExamplesThe azoles include:
A "dioxole" is a similar compound with two oxygen atoms in a five membered ring. Dioxolane is a derivative of dioxole. UsesMany azoles are used as antifungal drugs (azole antifungals), inhibiting the fungal enzyme 14α-demethylase which produces ergosterol. References |
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Azole". A list of authors is available in Wikipedia. |