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Ascofuranone
Ascofuranone is an antibiotic produced by the fungus Ascochyta visiae[1] that inhibits the Trypanosoma brucei alternative oxidase and is a lead compound in efforts to produce other drugs targeting this enzyme for the treatment of sleeping sickness.[2] The compound is effective both in vitro cell culture and in infections in mice.[1] Additional recommended knowledgeAscofuranone has also been reported to have anti-tumor activity,[3] and modulate the immune system.[4] References
Categories: Antibiotics | Terpenes and terpenoids |
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This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Ascofuranone". A list of authors is available in Wikipedia. |