Ariadne (psychedelic)

Ariadne (α-Et-DOM), or 4-methyl-2,5-dimethoxy-alpha-ethylphenethylamine, is a lesser-known psychedelic drug. It is an analog of 2C-D and DOM. Ariadne was first synthesized by Alexander Shulgin. In his book PIHKAL (Phenethylamines I Have Known and Loved), Shulgin reported testing Ariadne up to a dose of 32mg, and reported that it produces psychedelia and a bare threshold.^[1] Very little data exists about the pharmacological properties, metabolism, and toxicity of Ariadne in humans apart from Shulgin's limited testing.

Additional recommended knowledge

Daily Visual Balance Check

Essential Laboratory Skills Guide

Correct Test Weight Handling Guide: 12 Practical Tips

However, in more recent animal studies, α-Et-DOM was shown to produce stimulus generalisation in rats trained to respond to the drug MDMA.^[2] This suggests that while α-Et-DOM may lack hallucinogenic effects, it might potentially produce empathogenic effects similar to those of MDMA if used at higher dose ranges, beyond those trialled by Shulgin (the potency of α-Et-DOM in this study was similar to that of MDMA, 1.5mg/kg, which would equate to a dose of ~100mg in a human).

References

See also

• Phenethylamine
• Psychedelics, dissociatives and deliriants

Categorization