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Aprobarbital



Aprobarbital
Systematic (IUPAC) name
5-propan-2-yl-5-prop-2-enyl-1,3-diazinane-2,4,6-trione
Identifiers
CAS number 77-02-1
ATC code N05CA05
PubChem 6464
Chemical data
Formula C10H14N2O3 
Mol. mass 210.23 g/mol
Synonyms Aprobarbital, Oramon, Allylpropymal, Alurate, 5-Isopropyl-5-allylbarbituric acid
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

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Legal status
Routes  ?

Aprobarbital (Oramon) is a barbiturate derivative invented in the 1920s by Ernst Preiswerk. It has sedative, hypnotic and anticonvulsant properties, and was used primarily for the treatment of insomnia. [1] Aprobarbital was never as widely used as more common barbiturate derivatives such as phenobarbital and is now rarely prescribed as it has been replaced by newer drugs with a better safety margin.


References

  1. ^ Reddemann H, Turk E. Oramon poisoning in infancy and childhood. Observations on 12 aprobarbital poisonings (German). Das Deutsche Gesundheitswesen. 1966 May 12;21(19):878-81.


v • d • e
Barbiturates (N01AF, N03AA, N05CA)
v • d • e
Psycholeptics: hypnotics and sedatives (N05C)
BarbituratesPentobarbital - Amobarbital - Butobarbital - Barbital - Aprobarbital - Secobarbital - Talbutal - Vinylbital - Vinbarbital - Cyclobarbital - Heptabarbital - Reposal - Methohexital - Hexobarbital - Thiopental - Ethallobarbital - Allobarbital - Proxibarbal - Phenobarbital
AldehydesAcetylglycinamide chloral hydrate - Chloral hydrate - Chloralodol - Dichloralphenazone - Paraldehyde - Petrichloral
BenzodiazepineBrotizolam - Cinolazepam - Doxefazepam - Estazolam - Flunitrazepam - Flurazepam - Loprazolam - Lorazepam - Lormetazepam - Nitrazepam - Nimetazepam - Midazolam - Quazepam - Temazepam - Triazolam
PiperidinedioneGlutethimide - Methyprylon - Pyrithyldione
QuinazolinoneAfloqualone - Cloroqualone - Diproqualone - Etaqualone - Mebroqualone - Mecloqualone - Methaqualone - Methylmethaqualone
NonbenzodiazepineCL-218,872 - Eszopiclone - Indiplon - Necopidem - Pazinaclone - Saripidem - Suproclone - Suriclone - SX-3228 - Zaleplon - Zolpidem - Zopiclone
Melatonin receptorAgomelatine - Melatonin - Ramelteon
GHB TypeGABOB - GHB - GBL - 1,4-Butanediol
OtherApronal - Bromides - Bromisoval - Carbromal - Clomethiazole - Dexmedetomidine - Embutramide - Ethchlorvynol - Ethinamate - Hexapropymate - Methylpentynol - Niaprazine - Propiomazine - Scopolamine - Sulfonmethane - Trichloroethanol - Triclofos - Valerian - Valnoctamide
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Aprobarbital". A list of authors is available in Wikipedia.
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