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Phenazone



Phenazone
Systematic (IUPAC) name
1,2-dihydro-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one
Identifiers
CAS number 60-80-0
ATC code N02BB01
PubChem 2206
Chemical data
Formula C11H12N2O 
Mol. mass 188.226
SMILES search in eMolecules, PubChem
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

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Legal status
Routes  ?

Phenazone, or phenazon, is an analgesic. It is formed by reducing diortho-dinitrodiphenyl with sodium amalgam and methyl alcohol, or by heating diphenylene-ortho-dihydrazine with hydrochloric acid to 150 C. It crystallizes in needles which melt at 156 C. Potassium permanganate oxidizes it to pyridazine tetracarboxylic acid.

Contents

Synonyms

Analgesine, Antipyrine, Diméthyloxyquinazine, Oxydiméthylquinazine, Oxydiméthylquinizine, Pyrazoline

See also

Propyphenazone

Chimic Class

  • Pyrazole
  • Pyrazolinone

Pharmacology

Adverse effects

  • Allergy to pyrazolones
  • Nausea
  • Agranulocytosis
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Phenazone". A list of authors is available in Wikipedia.
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