My watch list

Anti-p62 antibodies

Autoantibody(s)
Anti-p62
Autoantigen Isoform	Nucleoporin 62kDA
Autoantigen gene	NUP62
Affected organ(s)	Bile Duct
Associated Disease(s)	Primary biliary cirrhosis
HLA associations	DR2 (weak)

Anti-p62 antibodies (AP62A) are found in a primary biliary cirrhosis.^[1] p62 is also more frequent in Stage IV primary biliary cirrhosis and is prognostic for severe disease.^[2]^[3] The autoantigen is the nucleoporin 62kDA protein.

Additional recommended knowledge

Don't let static charges disrupt your weighing accuracy

Recognize and detect the effects of electrostatic charges on your balance

Correct Test Weight Handling Guide: 12 Practical Tips

References

^ Wesierska-Gadek J, Hohenuer H, Hitchman E, Penner E (1996). "Autoantibodies against nucleoporin p62 constitute a novel marker of primary biliary cirrhosis". Gastroenterology 110 (3): 840-7. PMID 8608894.
^ Miyachi K, Hankins RW, Matsushima H, et al (2003). "Profile and clinical significance of anti-nuclear envelope antibodies found in patients with primary biliary cirrhosis: a multicenter study". J. Autoimmun. 20 (3): 247-54. PMID 12753810.
^ Invernizzi P, Selmi C, Ranftler C, Podda M, Wesierska-Gadek J (2005). "Antinuclear antibodies in primary biliary cirrhosis". Semin. Liver Dis. 25 (3): 298-310. doi:10.1055/s-2005-916321. PMID 16143945.

v • d • e Antibodies: autoantibodies
Anti-actin - Anti-apolipoprotein - Anti-cardiolipin - Anti-centromere - Anti-ganglioside - Anti-gp210 - Anti-mitochondrial antibodies - Anti-neutrophil cytoplasmic antibody - Anti-nuclear antibody - Anti-p62 - Anti-phopsholipid - Anti-sp100 - Anti-thrombin - Anti-topoisomerase - Anti-transglutaminase - Lupus anticoagulant - Rheumatoid factor -