Amidine

Amidines are a class of oxoacid derivatives.

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The oxoacid from which an amidine is derived must be of the form R_nE(=O)OH, where R is a substituent. The −OH group is replaced by an −NH₂ group and the =O group is replaced by =NR, giving amidines the general structure R_nE(=NR)NR₂.

When the parent oxoacid is a carboxylic acid, the resulting amidine is a carboxamidine, and has the following general structure:

Carboxamidines are frequently referred to simply as amidines, as they are the most commonly-encountered type of amidine in organic chemistry. The simplest amidine is acetamidine, CH₃C(=NH)NH₂.

Examples of amidines include DBU and diminazene.

References

• International Union of Pure and Applied Chemistry. "amidines". Compendium of Chemical Terminology Internet edition.
• International Union of Pure and Applied Chemistry. "carboxamidines". Compendium of Chemical Terminology Internet edition.
• International Union of Pure and Applied Chemistry. "sulfinamidines". Compendium of Chemical Terminology Internet edition.