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Alizapride



Alizapride
Systematic (IUPAC) name
N-[(1-allylpyrrolidin-2-yl)methyl]-6-methoxy-
1H-benzotriazole-5-carboxamide
Identifiers
CAS number 59338-93-1
ATC code A03FA05
PubChem 43008
Chemical data
Formula C16H21N5O2 
Mol. mass 315.37 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life 3 hours
Excretion Renal
Therapeutic considerations
Pregnancy cat.

?

Legal status
Routes Oral, intramuscular, intravenous

Alizapride is a dopamine antagonist with prokinetic and antiemetic effects used in the treatment of nausea and vomiting, including postoperative nausea and vomiting. It is structurally related to metoclopramide.[1]

Alizapride is marketed under various trade names including Plitican, Superan and Vergentan.[2]

References

  1. ^ Bleiberg H, Gerard B, Dalesio O, Crespeigne N, Rozencweig M (1988). "Activity of a new antiemetic agent: alizapride. A randomized double-blind crossover controlled trial". Cancer Chemother Pharmacol 22 (4): 316–20. PMID 3048762.
  2. ^ (French) Alizapride Chlorhydrate. BIAM (June 2 1997). Retrieved on 2007-08-14.


v • d • e
Drugs for functional gastrointestinal disorders (A03)
Drugs for functional bowel disordersantimuscarinics: Mebeverine - Dicycloverine - Propantheline

papaverine and derivatives: Papaverine - Drotaverine - Moxaverine

acting on serotonin receptors: 5-HT3 antagonists (Alosetron, Cilansetron) - 5HT4 agonists (Mosapride, Tegaserod)

other: Diisopromine - Isometheptene - Phloroglucinol - Proglumide - Tridihexethyl
Belladonna and derivatives
(antimuscarinics)		Atropine - Hyoscyamine - Butylscopolamine - Methylscopolamine
Propulsivesprimarily dopamine antagonists (Metoclopramide/Bromopride, Domperidone, Alizapride) - serotonin agonists (Cisapride) - Clebopride
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Alizapride". A list of authors is available in Wikipedia.
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