My watch list

Alglucerase

Alglucerase
Systematic (IUPAC) name
Human Beta-glucocerebrosidase
Identifiers
CAS number	37228-64-1
ATC code	A16AB01
PubChem	?
DrugBank	BTD00037
Chemical data
Formula	C₂₅₃₂H₃₈₅₄N₆₇₂O₇₁₁S₁₆
Mol. mass	55597.4 g/mol
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	3.6–10.4 min
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	?

Alglucerase is a modified form of human β-glucocerebrosidase where the non-reducing ends of the oligosaccharide chains have been terminated with mannose residues. Ceredase is a citrate buffered solution of Alglucerase manufactured by Genzyme Corporation from human placental tissue. It is given intravenously in the treatment of Type 1 Gaucher's disease although it has been largely replaced by Cerezyme® which is produced by Recombinant DNA technology.

Additional recommended knowledge

What is the Correct Way to Check Repeatability in Balances?

Better weighing performance in 6 easy steps

Correct Test Weight Handling Guide: 12 Practical Tips

v • d • e Other alimentary tract and metabolism products (A16)
Amino acids and derivatives	Levocarnitine - Ademetionine - Levoglutamide - Mercaptamine - Carglumic acid - Betaine
Enzymes	Alglucerase - Imiglucerase - Agalsidase alfa - Agalsidase beta - Laronidase - Sacrosidase - Alglucosidase alfa - Galsulfase - Idursulfase
Various alimentary tract and metabolism products	Tioctic acid - Anethole trithione - Sodium phenylbutyrate - Nitisinone - Zinc acetate - Miglustat