My watch list
my.chemeurope.com  

my.chemeurope.com

With an accout for my.chemeurope.com you can always see everything at a glance – and you can configure your own website and individual newsletter.

  • My watch list
  • My saved searches
  • My saved topics
  • My newsletter
Register free of charge
Login  
eng  
DeutschEnglishFrançaisEspañol

Acrivastine



Acrivastine
Systematic (IUPAC) name
(E)-3-{6-[(E)-1-(4-methylphenyl)-3-pyrrolidin-1-yl-
prop-1-enyl]pyridin-2-yl}prop-2-enoic acid
Identifiers
CAS number 87848-99-5
ATC code R06AX18
PubChem 5284514
Chemical data
Formula C22H24N2O2 
Mol. mass 348.438 g/mol
SMILES search in eMolecules, PubChem
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life 1.5 hours
Excretion Renal
Therapeutic considerations
Pregnancy cat.

?

Legal status
Routes  ?

Acrivastine is a medication used for the treatment of allergies and hay fever. It is a second-generation H1-receptor antagonist antihistamine and works by blocking H1 histamine receptors.

It is sold under the brand name Benadryl Allergy Relief in the U.K. by Pfizer, not to be confused with Benadryl Once a Day, which is cetirizine and is also sold by Pfizer in the U.K. This drug is currently not available as a generic in the U.K. [1]

In the U.S., acrivastine is the active ingrediant in the Semprex brand. Semprex-D is also acrivastine based, but also contains a decongestant.

References

  1. ^ Cheapest hayfever remedies 2007, Money Saving expert, May 15th,2007
v • d • e
Antihistamines (primarily R06)
Aminoalkyl ethersBromazine • Carbinoxamine • Clemastine • Chlorphenoxamine • Diphenylpyraline • Diphenhydramine • Doxylamine • Orphenadrine • Phenyltoloxamine
Substituted alkylaminesBrompheniramine • Chlorphenamine • Dexbrompheniramine • Dexchlorpheniramine • Dimetindene • Pheniramine • Talastine
Substituted ethylenediaminesChloropyramine • Histapyrrodine • Mepyramine • Methapyrilene • Tripelennamine (Pyribenzamine)
Phenothiazine derivativesAlimemazine • Hydroxyethylpromethazine • Isothipendyl • Mequitazine • Methdilazine • Oxomemazine • Promethazine
Piperazine derivativesBuclizine • Cetirizine • Chlorcyclizine • Cinnarizine • Cyclizine • Hydroxyzine • Levocetirizine • Meclizine • Niaprazine • Oxatomide
Others for systemic useAntazoline • Azatadine • Bamipine • Cyproheptadine • Deptropine • Dimebon • Ebastine • Epinastine • Ketotifen • Mebhydrolin • Mizolastine • Phenindamine • Pimethixene • Pyrrobutamine • Rupatadine • Triprolidine • selective (Acrivastine • Astemizole • Azelastine • Desloratadine • Fexofenadine • Loratadine • Terfenadine)
For topical useBamipine • Chloropyramine • Chlorphenoxamine • Clemastine • Dimetindene • Diphenhydramine • Isothipendyl • Mepyramine • Promethazine • Thenalidine
Antiallergic agents excluding corticosteroidsAntazoline • Azelastine
Other antiallergicsEmedastine • Epinastine • Ketotifen • Olopatadine
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Acrivastine". A list of authors is available in Wikipedia.
Your browser is not current. Microsoft Internet Explorer 6.0 does not support some functions on Chemie.DE