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Acetohydroxamic acid



Acetohydroxamic acid
Systematic (IUPAC) name
ethanehydroxamic acid
Identifiers
CAS number 546-88-3
ATC code G04BX03
PubChem 1990
DrugBank APRD00774
Chemical data
Formula C2H5NO2 
Mol. mass 75.0666 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

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Legal status
Routes  ?

Acetohydroxamic acid (also known as AHA or Lithostat) is a drug that is a potent and irreversible inhibitor of bacterial and plant urease usually used for urinary tract infections. The molecule is similar to urea but is not hydrolyzable by the urease enzyme (Fishbein and Carbone, 1965).

Notes

References J Biol Chem. 1965 Jun;240:2407-14. W. Fishbein and P. Carbone

 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Acetohydroxamic_acid". A list of authors is available in Wikipedia.
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