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Aceclidine


Aceclidine
Systematic (IUPAC) name
1-azabicyclo[2.2.2]oct-8-yl acetate
Identifiers
CAS number	827-61-2 (or 6109-70-2 [HCl])
ATC code	S01EB08
PubChem	1979
Chemical data
Formula	C₉H₁₅N O₂
Mol. mass	169.221 g/mol
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status	℞ Prescription only
Routes	Ocular

Aceclidine (INN) (trade names Glaucostat, Glaunorm, Glaudin) is a parasympathomimetic miotic agent used in the treatment of narrow angle glaucoma. It decreases intraocular pressure.

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Mechanism of action

Aceclidine acts primarily on the muscarinic receptor.

Side effects

Side effects of aceclidine include increased salivation, bradycardia (in excessive doses).

References

ACECLIDINE CHLORHYDRATE [Article in French] Biam. Last update: 2 September 1999. Accessed 13 September 2005 (UTC)
ACECLIDINE (АЦЕКЛИДИН) [Article in Russian] ViDAL 2005. Accessed 13 September 2005.

v • d • e Ophthalmologicals: antiglaucoma preparations and miotics (S01E)
Sympathomimetics	Apraclonidine • Brimonidine • Clonidine • Dipivefrine • Epinephrine
Parasympathomimetics	Aceclidine • Acetylcholine • Carbachol • Demecarium • Echothiophate • Stigmine (Fluostigmine, Neostigmine, Physostigmine) • Paraoxon • Pilocarpine
Carbonic anhydrase inhibitors	Acetazolamide • Brinzolamide • Diclofenamide • Dorzolamide • Methazolamide
Beta blocking agents	Befunolol • Betaxolol • Carteolol • Levobunolol • Metipranolol • Timolol
Prostaglandin analogues	Bimatoprost • Latanoprost • Travoprost • Unoprostone
Other agents	Dapiprazole • Guanethidine