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Aceclidine


Aceclidine
Systematic (IUPAC) name
1-azabicyclo[2.2.2]oct-8-yl acetate
Identifiers
CAS number	827-61-2 (or 6109-70-2 [HCl])
ATC code	S01EB08
PubChem	1979
Chemical data
Formula	C₉H₁₅N O₂
Mol. mass	169.221 g/mol
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status	℞ Prescription only
Routes	Ocular

Aceclidine (INN) (trade names Glaucostat, Glaunorm, Glaudin) is a parasympathomimetic miotic agent used in the treatment of narrow angle glaucoma. It decreases intraocular pressure.

Additional recommended knowledge

Essential Laboratory Skills Guide

How to ensure accurate weighing results every day?

How to quickly check pipettes?

Mechanism of action

Aceclidine acts primarily on the muscarinic receptor.

Side effects

Side effects of aceclidine include increased salivation, bradycardia (in excessive doses).

References

ACECLIDINE CHLORHYDRATE [Article in French] Biam. Last update: 2 September 1999. Accessed 13 September 2005 (UTC)
ACECLIDINE (АЦЕКЛИДИН) [Article in Russian] ViDAL 2005. Accessed 13 September 2005.

v • d • e Ophthalmologicals: antiglaucoma preparations and miotics (S01E)
Sympathomimetics	Apraclonidine • Brimonidine • Clonidine • Dipivefrine • Epinephrine
Parasympathomimetics	Aceclidine • Acetylcholine • Carbachol • Demecarium • Echothiophate • Stigmine (Fluostigmine, Neostigmine, Physostigmine) • Paraoxon • Pilocarpine
Carbonic anhydrase inhibitors	Acetazolamide • Brinzolamide • Diclofenamide • Dorzolamide • Methazolamide
Beta blocking agents	Befunolol • Betaxolol • Carteolol • Levobunolol • Metipranolol • Timolol
Prostaglandin analogues	Bimatoprost • Latanoprost • Travoprost • Unoprostone
Other agents	Dapiprazole • Guanethidine