Acatalasia

Additional recommended knowledge

What is the Sensitivity of my Balance?

What is the Correct Way to Check Repeatability in Balances?

Essential Laboratory Skills Guide

Acatalasia (also called acatalasemia, or Takahara's disease) is an autosomal recessive peroxisomal disorder caused by a complete lack of catalase.

The disorder is relatively benign, although it causes an increased incidence of periodontal infections, and can under rare circumstances lead to gangrene.^{[citation needed]}

History

In 1948 , Dr.Shigeo Takahara (1908-1994), a Japanese otolaryngologist first reported this new disease.^{[citation needed]} He had examined a patient with an oral ulcer. He had spread hydrogen peroxide on the diseased part, but oxygen was not generated due to the lack of catalase.